Balance, clarity, and renewed vitality.
Perimenopause and menopause can bring hot flashes, fatigue, brain fog, and changes in mood, sleep, and libido. AregoMD’s physician-guided hormone therapy is tailored to you—so you can feel steady, clear, and like yourself again.
View TreatmentsMenopause is universal. Real support isn't.
Every woman who lives long enough goes through menopause, yet far too many navigate it without guidance. Hormone therapy is one of the most studied tools in women's medicine — it's worth understanding your options.
Symptoms hormones can drive
If several of these sound familiar, a hormone imbalance may be the reason—and it’s treatable.
The biology behind the symptoms
Menopause isn't a single moment — it's a hormonal recalibration. As the ovaries wind down, several key hormones decline, and each one touches systems far beyond reproduction. Understanding the mechanism is the first step to addressing it.
Temperature, bone & mood
Estrogen helps regulate the brain's internal thermostat, preserves bone density, supports mood-stabilizing pathways, and keeps skin and tissues supple. As it falls, hot flashes, night sweats, low mood, and changes in skin and bone can follow.
Sleep & calm
Progesterone often declines earliest. It acts on the brain's calming GABA pathways and protects the uterine lining. Its loss is felt most in broken sleep, restlessness, and a harder time winding down at night.
Energy, drive & muscle
Often overlooked in women, these hormones support libido, motivation, and lean muscle. As they decline, many women notice flagging energy, reduced interest in intimacy, and shifts in body composition despite unchanged habits.
Why weight shifts in menopause
Many women find the habits that once kept them steady stop working in their 40s and 50s. That's not a willpower problem — it's a hormonal one.
Declining estrogen nudges the body to store more fat around the midsection and can slow resting metabolism, while a gradual loss of muscle makes energy harder to burn. When sleep, mood, and energy dip at the same time, it can feel like your body is working against you.
By restoring hormones toward a more balanced range, therapy can help remove some of these biological roadblocks — so healthy habits have a fair chance to work again.
Make Your Planweeks is a common window in which many women begin to notice relief from symptoms like hot flashes and disrupted sleep on a steady plan.
Timelines vary by individual and treatment. Some changes take longer, and your provider adjusts your plan over time.
Physician-prescribed options
Every option below is prescription-only and dispensed through certified U.S. pharmacies after a provider reviews your intake and labs. Start the intake for any treatment you’re interested in.
Bi-Est
Cream · 50:50 & 80:20
A compounded blend of estradiol and estriol that replenishes the two key estrogens together. It targets the root of hot flashes and night sweats while supporting mood, skin, and tissue comfort with a balanced approach.
- Hot flashes
- Night sweats
- Mood swings
- Vaginal dryness
- Disrupted sleep
- Skin & tissue changes
Bi-Est
Capsule · Bi-Est + Testosterone
A compounded blend of estradiol and estriol that replenishes the two key estrogens together. It targets the root of hot flashes and night sweats while supporting mood, skin, and tissue comfort with a balanced approach.
- Hot flashes
- Night sweats
- Mood swings
- Vaginal dryness
- Disrupted sleep
- Skin & tissue changes
DHEA
Capsule · 25 mg
A foundational precursor the body converts into both estrogen and testosterone. Replenishing it helps restore the raw material for energy, libido, and lean muscle that naturally declines with age.
- Low energy & fatigue
- Low libido
- Reduced muscle tone
- Low motivation
- Overall hormone balance
Estradiol
Insert
The most potent estrogen and the workhorse of menopausal relief. Delivered through the skin, it absorbs steadily into the bloodstream while bypassing first-pass liver metabolism — supporting temperature regulation, bone density, and overall wellbeing.
- Hot flashes
- Night sweats
- Bone protection
- Low mood
- Skin elasticity
- Temperature regulation
Estradiol
Patch
The most potent estrogen and the workhorse of menopausal relief. Delivered through the skin, it absorbs steadily into the bloodstream while bypassing first-pass liver metabolism — supporting temperature regulation, bone density, and overall wellbeing.
- Hot flashes
- Night sweats
- Bone protection
- Low mood
- Skin elasticity
- Temperature regulation
Estriol
Vaginal Insert · 1 mg
A milder, locally focused estrogen prized for genitourinary comfort. Applied where it is needed, it helps restore moisture, elasticity, and tissue health to ease dryness and discomfort.
- Vaginal dryness
- Discomfort with intimacy
- Tissue irritation
- Urinary comfort
Progesterone
Cream · 4%
Micronized, body-identical progesterone that calms the nervous system through GABA pathways to deepen sleep, while protecting the uterine lining and balancing the effects of estrogen.
- Poor or broken sleep
- Restlessness & anxiety
- Mood changes
- Uterine lining protection
Progesterone
Capsule · 100 mg
Micronized, body-identical progesterone that calms the nervous system through GABA pathways to deepen sleep, while protecting the uterine lining and balancing the effects of estrogen.
- Poor or broken sleep
- Restlessness & anxiety
- Mood changes
- Uterine lining protection
Testosterone
Cream · 1%
A carefully dosed cream addressing an often-overlooked piece of female hormonal health — supporting libido, motivation, energy, and the maintenance of lean muscle.
- Low libido
- Low energy
- Reduced motivation
- Lean muscle support
- Mental focus
Testosterone
Capsule
A carefully dosed cream addressing an often-overlooked piece of female hormonal health — supporting libido, motivation, energy, and the maintenance of lean muscle.
- Low libido
- Low energy
- Reduced motivation
- Lean muscle support
- Mental focus
From intake to your front door
A straightforward, physician-guided process built around your symptoms.
Share your story
Complete a focused online intake about your symptoms, history, and goals — in about 10 minutes.
Provider review
A licensed provider reviews your information, and labs if appropriate, to determine whether therapy is suitable for you.
Your personalized plan
If prescribed, your formulation is tailored to your needs and prepared by a certified U.S. pharmacy.
Ongoing care
Treatment ships discreetly to your door, and your provider adjusts your plan as your body responds.
Care built around you
Frequently asked questions
What is hormone therapy, and how does it help?
Hormone therapy replenishes hormones — primarily estrogen and progesterone, and sometimes testosterone or DHEA — that the body produces less of during the menopausal transition. Because these hormones influence sleep, mood, temperature regulation, bone health, and body composition, restoring them toward a more balanced range can ease many of the symptoms women experience.
Am I a candidate?
Many women with bothersome menopausal symptoms are candidates, but suitability is always determined individually. Generally, women within about 10 years of their last period and under 60 are often good candidates. A licensed provider reviews your symptoms and health history to decide whether therapy is appropriate for you.
Do I need lab work before starting?
Not always. Leading menopause guidance supports diagnosing the transition based on symptoms rather than labs alone. That said, baseline labs can add useful context, since some symptoms overlap with other conditions. If labs are helpful in your case, your provider will let you know.
What is the difference between bioidentical and synthetic hormones?
Bioidentical hormones are structurally identical to the hormones your body makes. Other hormone therapies may use different molecular structures with their own clinical considerations. The options offered here emphasize body-identical, micronized formulations such as estradiol, estriol, progesterone, DHEA, and testosterone when clinically appropriate.
How is my plan personalized?
There is no one-size-fits-all prescription. Based on your symptoms, history, and provider evaluation, your plan may combine creams, capsules, or inserts at doses chosen for your needs. Your provider can adjust the formulation over time as your body responds.
How soon will I notice a difference?
Many women begin to feel relief from symptoms like hot flashes and disrupted sleep within roughly 4 to 8 weeks of consistent use, though this varies. Some benefits build gradually over several months. Staying in touch with your provider helps fine-tune your results.
What are the possible side effects?
Side effects depend on the formulation and dose, and may include breast tenderness, bloating, headaches, spotting, mood changes, or irritation at an application site. Most are mild and often settle as your body adjusts. Always review risks and benefits with a medical professional.
Can I use this during perimenopause?
Hormonal needs in perimenopause can differ from those after menopause. Whether therapy is appropriate during this stage depends on your individual symptoms and history, which your provider will assess during your evaluation. If it is not the right fit, they will tell you.
Should I tell my primary care doctor?
Yes. Even though a licensed provider reviews and prescribes your therapy, your primary care physician knows your full medical history and can help ensure your overall care stays coordinated and safe.
Used responsibly, under provider guidance
Therapy may not be right for everyone
Hormone therapy is not appropriate for some individuals. Tell your provider if any of the following apply, as they may affect eligibility:
- A current or past hormone-sensitive cancer, or active cancer treatment
- A history of blood clots, stroke, or heart attack
- Significant liver disease
- Unexplained vaginal bleeding
- Known or suspected pregnancy
What to expect & report
Most side effects are mild and tend to ease over time. Contact a medical professional if you experience anything concerning. Possible effects include:
- Breast tenderness or bloating
- Headaches or nausea
- Spotting or changes in bleeding
- Mood changes
- Skin irritation at an application site
This page is for general education and is not medical advice. The lists above are not comprehensive. Treatment eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness, and not everyone will qualify. Prescription products are dispensed through certified U.S. pharmacies. Compounded medications are prepared by a licensed pharmacy and are not FDA-approved. Individual results vary. Always consult a licensed healthcare professional before starting any treatment, and call your local emergency number if you have a medical emergency.
Ready to feel like yourself again?
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